Van Goozen S H, Cohen-Kettenis P T, Gooren L J, Frijda N H, Van de Poll N E
Department of Child and Adolescent Psychiatry, University Hospital Utrecht, The Netherlands.
Neuropsychologia. 1994 Oct;32(10):1153-7. doi: 10.1016/0028-3932(94)90099-x.
It is still unclear whether sex differences in cognitive functioning are mainly due to perinatal organizing effects of sex hormones on the brain, or to activating effects in adulthood. In a group of 22 female-to-male transsexuals a battery of visuospatial and verbal ability tests was administered twice: shortly before and 3 months after the start of androgen treatment. The administering of androgens was clearly associated with an increase in spatial ability performance. In contrast, it had a deteriorating effect on verbal fluency tasks. This study offers preliminary evidence that androgens directly and quickly affect cognitive performance in females.
认知功能的性别差异主要是由于性激素在围产期对大脑的组织作用，还是成年期的激活作用，目前仍不清楚。在一组22名女性变男性的变性者中，进行了一系列视觉空间和语言能力测试，测试进行了两次：在雄激素治疗开始前不久和开始3个月后。雄激素的施用明显与空间能力表现的提高有关。相比之下，它对语言流畅性任务有恶化作用。这项研究提供了初步证据，表明雄激素直接且迅速地影响女性的认知表现。
