Pedersen K M, Iversen E, Laurberg P
Department of Internal Medicine and Endocrinology, Aalborg Hospital, Denmark.
Eur J Endocrinol. 1995 Feb;132(2):171-4. doi: 10.1530/eje.0.1320171.
Several studies have demonstrated that the iodine intake is relatively low in Denmark. However, the results are difficult to interpret because no information has been given on the frequency of individual iodine supplementation. We performed a cross-sectional study of elderly subjects living in the commune of Randers, Denmark. Urinary iodine excretion was measured in the 423 participants (185 males, 238 females) and a careful history was taken on any possible intake of supplementary iodine. The median urinary iodine excretion was 48.3 micrograms/g creatinine for the whole population (40.8 micrograms/g creatinine in males, 53.2 micrograms/g creatinine in females). In the part of the population that did not take iodine supplementation (46.7%) the median value was 36.1 micrograms/g creatinine (males 33.8; females 38.8). Regular iodine supplementation taken as an iodine-containing vitamin/mineral tablet was found in 30.8% of the population. This increased the urinary iodine excretion to a median level of 80.5 micrograms/g creatinine (males 62.0; females 88.0). The study shows that the basic iodine intake level is overestimated if individual iodine supplementation is not taken into account. Such supplementation may lead to median iodine excretion values that seem reasonable, even if the iodine intake of the part of the population not taking iodine (in this study, nearly half of the population) is low.
多项研究表明，丹麦的碘摄入量相对较低。然而，这些结果难以解读，因为未提供关于个体碘补充剂使用频率的信息。我们对丹麦兰讷斯公社的老年受试者进行了一项横断面研究。测量了423名参与者（185名男性，238名女性）的尿碘排泄量，并仔细询问了任何可能的碘补充剂摄入情况。整个人群的尿碘排泄中位数为48.3微克/克肌酐（男性为40.8微克/克肌酐，女性为53.2微克/克肌酐）。在未服用碘补充剂的人群部分（46.7%）中，中位数为36.1微克/克肌酐（男性33.8；女性38.8）。在30.8%的人群中发现有规律地服用含碘维生素/矿物质片作为碘补充剂。这使尿碘排泄量增加到中位数水平80.5微克/克肌酐（男性62.0；女性88.0）。该研究表明，如果不考虑个体碘补充剂的使用情况，基本碘摄入量水平会被高估。这种补充剂可能会导致碘排泄中位数看起来合理，即使未服用碘的人群部分（在本研究中，几乎占一半人群）的碘摄入量较低。
