Nøhr S B, Laurberg P, Børlum K G, Pedersen K M, Johannesen P L, Damm P, Fuglsang E, Johansen A
Department of Internal Medicine and Endocrinology, Aalborg Hospital.
Acta Obstet Gynecol Scand. 1993 Jul;72(5):350-3. doi: 10.3109/00016349309021111.
Iodine requirements are increased during pregnancy and lactation and adequate iodine intake is important for normal brain development of the fetus/newborn child. The aim of the present study was to evaluate the extent to which this increase in iodine requirement is met in pregnant women living in various regions of Denmark. One hundred and fifty-two healthy pregnant women admitted to five different Danish departments of obstetrics participated in the study. Iodine status was evaluated by measurement of iodine in spot urine at day five after delivery and by careful history of the intake of iodine containing vitamin/mineral tablets. Approximately one third of the women had received tablets containing iodine. In women who had not received iodine supplementation urinary iodine was low with a median value of 39.7 micrograms/g creatinine (Aalborg 28, Randers 33, Ringkøbing 34, Arhus 43 and Copenhagen 62 micrograms/g creatinine). These values are far below internationally recommended levels. The consequences remain to be evaluated and no firm recommendations can be given. It seems reasonable, however, to recommend a high intake of food containing iodine (e.g. milk products) during pregnancy and lactation. Since nearly all the women took some kind of vitamin/mineral supplementation it could be considered to advocate intake of vitamin/mineral tablets containing iodine.
孕期和哺乳期对碘的需求量会增加，充足的碘摄入对胎儿/新生儿的正常脑发育至关重要。本研究的目的是评估丹麦不同地区的孕妇对碘需求增加的满足程度。152名入住丹麦五个不同产科科室的健康孕妇参与了该研究。通过测量产后第5天的随机尿碘以及仔细询问含碘维生素/矿物质片的摄入情况来评估碘状况。约三分之一的女性服用过含碘片剂。未补充碘的女性尿碘水平较低，中位数为39.7微克/克肌酐（奥尔堡为28，兰讷斯为33，灵克宾为34，奥胡斯为43，哥本哈根为62微克/克肌酐）。这些数值远低于国际推荐水平。其后果仍有待评估，目前无法给出确切建议。然而，在孕期和哺乳期推荐高碘食物（如奶制品）的摄入似乎是合理的。由于几乎所有女性都服用某种维生素/矿物质补充剂，因此可以考虑提倡摄入含碘的维生素/矿物质片。
