Tinkanen H, Kujansuu E, Laippala P
Department of Obstetrics and Gynecology, University of Tampere, Finland.
Eur J Obstet Gynecol Reprod Biol. 1994 Nov;57(2):111-5. doi: 10.1016/0028-2243(94)90052-3.
In this study we investigated the blood flow in uterine (u.a.) and ovarian arteries (o.a.) in healthy women and infertility patients and the relationship of vascular resistance to the etiology and the prognosis of infertility. A total of 101 consecutive infertility patients referred to hospital for investigations were studied by Doppler ultrasound. Couples with male infertility were excluded. The control group comprised 19 healthy women having regular menstrual cycle and no history of infertility. The pulsatility index (PI) in o.a. and u.a. was measured in pre- and post-ovulatory phase of the menstrual cycle. The PI values of the controls were compared with those of the patients with various infertility etiologies. The PI values of the infertility patients who subsequently delivered were compared with those of the patients failing to deliver. Infertility patients had high PI in o.a. and u.a. in the luteal phase more often than controls. High vascular resistance in u.a. and o.a. in the luteal phase reduce the take-baby-home rate.
在本研究中,我们调查了健康女性和不孕患者子宫动脉(u.a.)及卵巢动脉(o.a.)的血流情况,以及血管阻力与不孕病因和预后的关系。通过多普勒超声对总共101名连续转诊至医院进行检查的不孕患者进行了研究。排除了男性不育的夫妇。对照组由19名月经周期规律且无不孕史的健康女性组成。在月经周期的排卵前和排卵后阶段测量卵巢动脉和子宫动脉的搏动指数(PI)。将对照组的PI值与各种不孕病因患者的PI值进行比较。将随后分娩的不孕患者的PI值与未分娩患者的PI值进行比较。不孕患者在黄体期卵巢动脉和子宫动脉的PI值高于对照组的情况更为常见。黄体期子宫动脉和卵巢动脉的高血管阻力会降低抱婴回家率。