Jekabsons W, Schuster W
Institut für Genbiologische Forschung, Berlin, Germany.
Mol Gen Genet. 1995 Jan 20;246(2):166-73. doi: 10.1007/BF00294679.
A highly transcribed region in Oenothera mitochondria codes for an open reading frame comprising 250 condons (orf250). This open reading frame shows high sequence similarity to the helC gene of Rhodobacter capsulatus which encodes a subunit of a proposed ABC-type heme transporter. Transcripts of orf250 are edited by cytidine to uridine transitions at 29 sites, altering 10% of all encoded amino acids. Genes homologous to helC have also been found in the bacteria Bradyrhizobium japonicum and Escherichia coli, and are conserved in mitochondria of Marchantia polymorpha, Daucus carota, and Arabidopsis thaliana. In bacteria these genes belong to operons that are involved in the biogenesis of c-type cytochromes. The bacterial gene organization is partly conserved in Marchantia, but altered in the mitochondrial genome of Oenothera.
月见草属线粒体中的一个高转录区域编码一个由250个密码子组成的开放阅读框（orf250）。这个开放阅读框与荚膜红细菌的helC基因具有高度的序列相似性，后者编码一种推测的ABC型血红素转运蛋白的一个亚基。orf250的转录本在29个位点通过胞嘧啶向尿嘧啶的转变进行编辑，改变了所有编码氨基酸的10%。在细菌大豆慢生根瘤菌和大肠杆菌中也发现了与helC同源的基因，并且在多歧银叶苔、胡萝卜和拟南芥的线粒体中保守。在细菌中，这些基因属于参与c型细胞色素生物合成的操纵子。细菌的基因组织在银叶苔中部分保守，但在月见草属的线粒体基因组中发生了改变。
