植物线粒体中一个保守阅读框的RNA编辑增加了其与大肠杆菌中两个重叠阅读框的相似性。
RNA editing of a conserved reading frame in plant mitochondria increases its similarity to two overlapping reading frames in Escherichia coli.
作者信息
Sünkel S, Brennicke A, Knoop V
机构信息
Institut für Genbiologische Forschung, Berlin, Germany.
出版信息
Mol Gen Genet. 1994 Jan;242(1):65-72. doi: 10.1007/BF00277349.
An open reading frame (orfx) in mitochondria of the higher plants Oenothera berteriana and Arabidopsis thaliana is homologous to orf244 in the mitochondrial genome of Marchantia polymorpha. Homologous sequences are also present in carrot, potato and sugar beet. Profile analysis revealed similarity to two overlapping reading frames in the Escherichia coli genome. Potential translation initiation at conserved ATA (isoleucine) and TTG (leucine) codons is discussed. Transcripts of the open reading frame are altered by RNA editing in Arabidopsis and Oenothera downstream of these codons, suggesting this to be the functionally important region.
在高等植物月见草和拟南芥的线粒体中，一个开放阅读框（orfx）与地钱线粒体基因组中的orf244同源。胡萝卜、马铃薯和甜菜中也存在同源序列。轮廓分析显示其与大肠杆菌基因组中的两个重叠阅读框相似。文中讨论了在保守的ATA（异亮氨酸）和TTG（亮氨酸）密码子处潜在的翻译起始。在拟南芥和月见草中，这些密码子下游的开放阅读框转录本会通过RNA编辑发生改变，这表明该区域具有重要的功能。
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