Scheie A A
Department of Oral Biology, Dental Faculty, University of Oslo, Norway.
Adv Dent Res. 1994 Jul;8(2):246-53. doi: 10.1177/08959374940080021801.
Much effort has been placed on elucidating the diverse mechanisms of microbial adhesion to tooth surfaces. Both specific and non-specific types of adhesion have been envisaged. Pioneer colonizers represent a selected part of the oral microflora, and it has been assumed that specific adhesin-receptor interactions between the microbial surface and the pellicle account for this specificity. Whereas microbial adhesion to tooth surfaces is a general prerequisite for initiation of plaque formation, microbial multiplication is probably the dominant feature in the build-up of dental plaque. Local environmental factors which influence the establishment and composition of the ultimate plaque community are therefore of greater importance than initial adhesion per se. The highly individual and site-related characteristics of the plaque flora illustrate the selective power of the environment. Environmental conditions are not uniform. Thus, each site represents its own conditions are not uniform. Thus, each site represents its own distinct ecosystem, and the microbial composition at the site depends on the outcome of a variety of host-microbial and microbial-microbial interactions. The relative in vivo significance of these interactions is difficult to assess.
人们在阐明微生物黏附于牙齿表面的多种机制方面付出了诸多努力。已经设想了特异性和非特异性黏附类型。早期定植菌代表了口腔微生物群的一部分，并且据推测，微生物表面与获得性膜之间的特异性黏附素-受体相互作用解释了这种特异性。虽然微生物黏附于牙齿表面是菌斑形成起始的一般前提条件，但微生物增殖可能是牙菌斑形成过程中的主要特征。因此，影响最终菌斑群落建立和组成的局部环境因素比初始黏附本身更为重要。菌斑菌群高度个体化和部位相关的特征说明了环境的选择作用。环境条件并不一致。因此，每个部位都代表着其自身独特的生态系统，该部位的微生物组成取决于多种宿主-微生物和微生物-微生物相互作用的结果。这些相互作用在体内的相对重要性难以评估。
