Fitzsimmons R J, Ryaby J T, Magee F P, Baylink D J
Department of Medicine, Loma Linda University, California.
Calcif Tissue Int. 1994 Nov;55(5):376-80. doi: 10.1007/BF00299318.
Low energy electromagnetic fields (EMF) exhibit a large number of biological effects. A major issue to be determined is "What is the lowest threshold of detection in which cells can respond to an EMF?" In these studies we demonstrate that a low-amplitude combined magnetic field (CMF) which induces a maximum potential gradient of 10(-5) V/m is capable of increasing net calcium flux in human osteoblast-like cells. The increase in net calcium flux was frequency dependent, with a peak in the 15.3-16.3 Hz range with an apparent bandwidth of approximately 1 Hz. A model that characterizes the thermal noise limit indicates that non-spherical cell shape, resonant type dynamics, and signal averaging may all play a role in the transduction of low-amplitude EMF effects in biological systems.
低能量电磁场（EMF）具有大量生物效应。一个有待确定的主要问题是“细胞能够对EMF作出反应的最低检测阈值是多少？”在这些研究中，我们证明，诱导出最大电位梯度为10^(-5) V/m的低振幅组合磁场（CMF）能够增加人成骨样细胞中的净钙通量。净钙通量的增加与频率有关，在15.3 - 16.3 Hz范围内出现峰值，表观带宽约为1 Hz。一个表征热噪声极限的模型表明，非球形细胞形状、共振型动力学和信号平均可能都在生物系统中低振幅EMF效应的转导中发挥作用。
