沙美特罗气雾剂与沙丁胺醇气雾剂在哮喘患者中的比较。
Comparison of salmefamol with salbutamol aerosols in asthamatics.
作者信息
Sillett R W, Dash C H, McNicol M W
出版信息
Eur J Clin Pharmacol. 1976 Feb 6;9(4):277-80. doi: 10.1007/BF00561660.
PMID:786693
Abstract
In twelve asthmatic patients 200 mug of salmefamol and salbutamol given by metered aerosol produced a similar initial effect on FEV1, FVC and PEFR without significant effect on heart rate or blood pressure. The duration of effect of salbutamol was approximately 4 hours; there was still an appreciable effect from salmefamol at 8 hours.
摘要
在12名哮喘患者中，通过定量气雾剂给予200微克的沙美特罗和沙丁胺醇，对第一秒用力呼气量（FEV1）、用力肺活量（FVC）和呼气峰值流速（PEFR）产生了相似的初始效应，对心率和血压无显著影响。沙丁胺醇的作用持续时间约为4小时；8小时时沙美特罗仍有明显作用。
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