Hu L, Umeda A, Kondo S, Amako K
Department of Bacteriology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
J Med Microbiol. 1995 Feb;42(2):127-32. doi: 10.1099/00222615-42-2-127.
Colonisation by Staphylococcus aureus in the nares of 120 outpatients and 63 healthy adults was studied for c. 2 years. Two states of carriage of S. aureus were confirmed: persistent carriage and persistent non-carriage. The states of carriage and non-carriage were quite stable and > 60% of the population of any of the study groups were stable non-carriers. The results of typing the strains isolated from the same individuals at different times with DNA fingerprinting by digestion with SmaI enzyme showed that all the stable carriers were persistently infected with the same strain and that changes in the strain seldom occurred.
对120名门诊患者和63名健康成年人的鼻腔进行了约2年的金黄色葡萄球菌定植研究。确认了金黄色葡萄球菌的两种携带状态：持续携带和持续不携带。携带和不携带状态相当稳定，任何研究组中超过60%的人群是稳定的非携带者。用SmaI酶消化进行DNA指纹图谱分析，对不同时间从同一受试者分离的菌株进行分型，结果表明，所有稳定携带者均持续感染同一菌株，菌株很少发生变化。
