梅毒新血清学检测——反应素筛查的评估
Evaluation of reagin screen, a new serological test for syphilis.
作者信息
Dyckman J D, Wende R D, Gantenbein D, Williams R P
出版信息
J Clin Microbiol. 1976 Aug;4(2):145-50. doi: 10.1128/jcm.4.2.145-150.1976.
A total of 1,020 serum and plasma specimens were tested using the Venereal Disease Research Laboratory (VDRL), Rapid Plasma Reagin (RPR) card, Reagin Screen (RST) and Fluorescent Treponemal Antibody-Absorption (FTA-ABS) tests. In 257 normal patients, all screening tests were nonreactive; the FTA-ABS test was reactive for one patient. In 588 patients with treated and untreated syphilis, the RST results were 91.7% in agreement with the VDRL and RPR results. In 175 patients with diseases that cause biological false reactions, the RST was 94% in agreement with the other screening tests. The titer of the RST was within one dilution of the corresponding VDRL titer in 91.7% of the 360 speciments tested and within one dilution of the RPR titer in 96.9% of 358 specimens quantitated by both tests.
总共使用性病研究实验室（VDRL）、快速血浆反应素（RPR）卡片试验、反应素筛查（RST）和荧光密螺旋体抗体吸收（FTA - ABS）试验对1020份血清和血浆标本进行了检测。在257名正常患者中，所有筛查试验均为阴性；FTA - ABS试验有1名患者呈阳性。在588名已治疗和未治疗梅毒的患者中，RST结果与VDRL和RPR结果的一致性为91.7%。在175名患有可导致生物学假阳性反应疾病的患者中，RST与其他筛查试验的一致性为94%。在360份接受检测的标本中，91.7%的RST滴度与相应的VDRL滴度相差不超过一个稀释度；在358份同时进行两种试验定量检测的标本中，96.9%的RST滴度与RPR滴度相差不超过一个稀释度。
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