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[Effect of trans-anethole on liver monooxygenase system and its induction of polychlorinated diphenyls].

作者信息

Sinitskaia Z F, Lashneva N V, Chichilanova G V, Gadzhieva Z M, Shatrov G N, Tutelían V A

出版信息

Vopr Pitan. 1994(5):24-7.

PMID:7871771
Abstract

Effect of trans-anetol (t-An) as nutritive addition to cytochrome P-450 containing system (MOS) of liver of rats was studied. It was shown, that t-An rendered inducing action to MOS, which depended on degree of action. It was established that simultaneous effect of t-An and mixture of polychlorinated diphenyles (sovol) modified inducing action of sovol to cytochrome P-450 system, Simultaneous effect of t-An and mixture of polychlorinated diphenyles increased hepatotoxic action of these xenobiotics.

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