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DNA analysis with flow cytometry and image cytometry in colorectal polyps.

作者信息

Torresan F, Zanella L, Mattarozzi A, Quiroga A, Bacchini P, Bertoni F, Gandolfi L

机构信息

Department of Gastroenterology, Polyclinic Hospital S. Orsola-Malpighi, Bologna, Italy.

出版信息

Surg Endosc. 1994 Dec;8(12):1412-6. doi: 10.1007/BF00187347.

DOI:10.1007/BF00187347
PMID:7878508
Abstract

Ploidy was studied with flow and image cytometry in 51 polyps removed endoscopically from 44 patients. Evaluation was carried out on frozen material in 34 cases and on material fixed in formalin and embedded in paraffin in the remaining 17. Data analysis showed a statistically significant correlation between polyp size and aneuploidy frequency (P > 0.05). No statistically significant correlation was found between aneuploidy frequency and histological type. The linear correlation study did, however, show a correlation tendency between histological type and aneuploidy (R = 0.42211).

摘要

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本文引用的文献

1
Early detection of malignancy in ulcerative colitis. A flow-cytometric DNA study.溃疡性结肠炎中恶性肿瘤的早期检测。一项流式细胞术DNA研究。
Cancer. 1984 Jan 15;53(2):291-5. doi: 10.1002/1097-0142(19840115)53:2<291::aid-cncr2820530218>3.0.co;2-b.
2
Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.使用流式细胞术分析石蜡包埋病理材料细胞DNA含量的方法。
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3
A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis.
一种用于制备细胞核以进行流式细胞术DNA分析的去污剂-胰蛋白酶法。
Cytometry. 1983 Mar;3(5):323-7. doi: 10.1002/cyto.990030503.
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Flow cytometric detection of aneuploidy in colorectal adenomas.流式细胞术检测大肠腺瘤中的非整倍体
Cancer Res. 1985 Jul;45(7):3392-7.
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DNA aneuploidy in colorectal adenomas.结直肠腺瘤中的DNA非整倍体
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Association of DNA index and S-phase fraction with prognosis of nodes positive early breast cancer.
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The prognostic value of DNA ploidy combined with histologic substaging for incidental carcinoma of the prostate gland.
Am J Clin Pathol. 1988 Mar;89(3):370-3. doi: 10.1093/ajcp/89.3.370.
8
The predictive value of flow cytometric information in the clinical management of stage O (Ta) bladder cancer.流式细胞术信息在O期(Ta)膀胱癌临床管理中的预测价值。
J Urol. 1988 Feb;139(2):279-82. doi: 10.1016/s0022-5347(17)42386-x.
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Prognostic significance of DNA index, multiploidy, and S-phase fraction in ovarian cancer.DNA指数、倍体及S期分数在卵巢癌中的预后意义
Cancer. 1988 Jan 15;61(2):334-9. doi: 10.1002/1097-0142(19880115)61:2<334::aid-cncr2820610224>3.0.co;2-m.
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Value of DNA image cytometry in the prediction of malignant change in Barrett's oesophagus.DNA图像细胞术在预测巴雷特食管恶变中的价值。
Gut. 1989 Jul;30(7):899-905. doi: 10.1136/gut.30.7.899.