Desensitizing effects of Gluma and Gluma 2000 on hypersensitive dentin.

The aim of this clinical trial was to investigate the effects of topical applications of Gluma 3 Primer or Gluma 2000 conditioning solutions on hypersensitive erosion/abrasion lesions. Thirty-four patients were included in the trial with at least two teeth each presenting severe sensitivity. From a total of 116 teeth, 40 were treated with Gluma 3 Primer, 42 with Gluma 2000 Conditioner and 34 served as the control. Sensitivity was recorded as response to tactile and cold air stimuli prior to treatment as baseline, immediately after the topical application of the agents, after 1 week, 1 month and 6 months. Both Gluma groups showed a highly significant reduction in sensitivity between baseline and postoperative pain scores (P < 0.05) and between the postoperative and the 1-week responses (P < 0.05). The sensitivity scores were not different between 1 week and 6 months. In the control group, no pain reduction was registered between baseline and up to 1-month recall. After 6 months, however, the sensitivity was spontaneously slightly reduced. At the end of the 6-month observation time, 29 Gluma and 31 Gluma 2000 treated teeth no longer showed dentin sensitivity.