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低粘度玻璃离子与含戊二醛的树脂基底漆治疗牙本质过敏症的疗效比较——一项为期25.2个月的评估。

Comparison between effectiveness of a low-viscosity glass ionomer and a resin-based glutaraldehyde containing primer in treating dentine hypersensitivity--a 25.2-month evaluation.

作者信息

Polderman R N, Frencken J E

机构信息

Department of Preventive and Restorative Dentistry, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

出版信息

J Dent. 2007 Feb;35(2):144-9. doi: 10.1016/j.jdent.2006.06.005. Epub 2006 Sep 14.

Abstract

OBJECTIVES

The null-hypothesis tested was; there is no difference in effectiveness between a new low-viscosity glass ionomer and a resin-based glutaraldehyde containing primer in treating hypersensitive teeth after 2 years.

METHODS

Using a split-mouth design, hypersensitive teeth in 14 adult patients were randomly assigned to 2 treatment groups. Hypersensitive tooth surfaces were covered with a low-viscosity glass ionomer (Fuji VII) and a resin-based glutaraldehyde containing primer (Gluma Desensitizer). The discomfort interval scale (DIS) ranging from 0 to 4 was used to test the level of hypersensitivity before and after treatment, and at 3 months using compressed air blown for 2 s, and at 1 and 25.2 months using a telephone interview. Differences between and within the treatment groups were tested using the sign rank test.

RESULTS

Evaluations in the gluma group were discontinued after 3 months. The mean DIS score for hypersensitive teeth in the glass ionomer group was statistically significantly lower than that in the gluma group, immediately after application (p=0.0005), after 1 month (p=0.02) and after 3 months (p=0.003). After 3 months, 11/14 of the hypersensitive teeth in the glass ionomer group and 2/14 in the gluma group were free of sensitivity. The mean DIS score for hypersensitive teeth in the glass ionomer group remained low after 19.2 months (0.25: S.E.=0.13) and 25.2 months (0.22: S.E.=0.15).

CONCLUSIONS

The null-hypothesis was rejected. The low-viscosity glass ionomer (Fuji VII) is more effective in treating hypersensitive teeth than Gluma Desensitizer after 3 months. The positive treatment effect of the glass ionomer continued until 25.2 months.

摘要

目的

所检验的零假设为:在治疗两年后,新型低粘度玻璃离子体与含戊二醛的树脂基底漆在治疗牙齿过敏方面的有效性无差异。

方法

采用双侧设计,将14名成年患者的过敏牙齿随机分为两个治疗组。用低粘度玻璃离子体(富士VII型)和含戊二醛的树脂基底漆(Gluma脱敏剂)覆盖过敏牙齿表面。使用范围为0至4的不适间隔量表(DIS)在治疗前后、3个月时使用压缩空气吹2秒进行测试,以及在1个月和25.2个月时通过电话访谈进行测试。使用符号秩检验来检验治疗组之间和组内的差异。

结果

Gluma组在3个月后停止评估。在应用后即刻(p = 0.0005)、1个月后(p = 0.02)和3个月后(p = 0.003),玻璃离子体组过敏牙齿的平均DIS评分在统计学上显著低于Gluma组。3个月后,玻璃离子体组14颗过敏牙齿中有11颗、Gluma组14颗中有2颗不再敏感。玻璃离子体组过敏牙齿的平均DIS评分在19.2个月(0.25:标准误 = 0.13)和25.2个月(0.22:标准误 = 0.15)后仍保持较低水平。

结论

零假设被拒绝。3个月后,低粘度玻璃离子体(富士VII型)在治疗牙齿过敏方面比Gluma脱敏剂更有效。玻璃离子体的积极治疗效果持续到25.2个月。

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