Kakaboura Afrodite, Rahiotis Christos, Thomaidis Socratis, Doukoudakis Spyridon
Department of Operative Dentistry, Faculty of Dentistry, University of Athens, 2 Thivon Str, 115 27 Goudi, Athens, Greece.
Am J Dent. 2005 Aug;18(4):291-5.
To investigate the desensitizing ability of a one-bottle bonding agent and a glutaraldehyde-based HEMA formulation on sensitive tooth cervical areas for a period up to 9 months.
The sample consisted of 40 patients with cervical hypersensitivity. Three sensitive teeth per patient were treated; one received One-Step (one-bottle bonding agent), the other Gluma Desensitizer (glutaraldehyde-based agent) and the third distilled water (control group). The hypersensitivity level was determined before, immediately after the desensitizing session, at 8 weeks, and 9 months post-treatment. Measurements of sensitivity were determined by the patient's response to tactile and air-blast stimuli. A verbal rating scale was used and scored as follows: 0, no discomfort; 1, discomfort but no severe pain; 2, severe pain during simulation; 3, severe pain after simulation. The results were subjected to statistical analysis by Kruskal-Wallis test (a=0.05).
Both treatment procedures resulted in reduction of hypersensitivity to both stimuli, for up to 9 months. No significant differences were recorded between One-Step and Gluma Desensitizer at immediate and 8-week examinations, whereas Gluma Desensitizer produced lower hypersensitivity than One-Step at the 9-month assessment. In general, a lower level of reduction was found for the 9-month interval compared to the 8-week hypersensitivity score for both agents tested. A placebo effect was observed with water treatment, ranging from 4.7 to 27.5% reduction of hypersensitivity.
研究一种单瓶粘结剂和一种基于戊二醛的甲基丙烯酸羟乙酯配方对敏感牙齿颈部区域长达9个月的脱敏能力。
样本包括40例颈部过敏患者。每位患者的三颗敏感牙齿接受治疗；一颗接受单步粘结剂（One-Step），另一颗接受Gluma脱敏剂（基于戊二醛的制剂），第三颗接受蒸馏水（对照组）。在脱敏治疗前、治疗后立即、8周和9个月时测定过敏水平。通过患者对触觉和吹气刺激的反应来确定敏感性测量值。使用语言评定量表，评分如下：0，无不适；1，不适但无剧痛；2，模拟过程中剧痛；3，模拟后剧痛。结果采用Kruskal-Wallis检验进行统计分析（α=0.05）。
两种治疗方法均使两种刺激的过敏反应降低，长达9个月。在即刻和8周检查时，单步粘结剂和Gluma脱敏剂之间未记录到显著差异，而在9个月评估时，Gluma脱敏剂产生的过敏反应低于单步粘结剂。总体而言，与测试的两种制剂的8周过敏评分相比，9个月间隔的降低水平较低。用水治疗观察到安慰剂效应，过敏反应降低幅度为4.7%至27.5%。
