Dondi dall'Orologio G, Lorenzi R, Anselmi M, Opisso V
Dental School, University of Bologna, Italy.
Am J Dent. 1999 Jun;12(3):103-6.
To evaluate the effects of topical applications of Gluma Alternate, a Gluma Desensitizer version with reduced glutaraldehyde content, Health-Dent Desensitizer and Scotchbond Multi-Purpose (SMP) on hypersensitive erosion/abrasion lesions.
55 patients were included in the trial with at least three teeth each presenting severe sensitivity. From a total of 184 teeth, 69 were treated with Gluma Alternate, 58 with Health Dent and 51 treated SMP, serving as a control. Sensitivity was recorded as response to cold air stimulus prior to treatment, immediately after the topical application of the agents, and after 1 week, 1 month and 6 months.
Both Gluma Alternate and SMP showed significant reduction in sensitivity between pre- and postoperative pain scores (P < 0.05). The post-treatment sensitivity scores (0 and 1) were no different between 1 week and 6 months. In the Health-Dent group only 10 of the 58 teeth showed sensitivity reduction. For this reason the remaining 48 teeth received a "rescue treatment" with Gluma Desensitizer. At the end of the 6-month observation time, all teeth treated with Gluma Alternate, Gluma Desensitizer, and SMP showed no or very little dentin sensitivity.
评估Gluma Alternate(一种戊二醛含量降低的Gluma脱敏剂版本)、Health-Dent脱敏剂和Scotchbond多功能粘结剂(SMP)局部应用于过敏性侵蚀/磨损病变的效果。
55名患者纳入试验,每人至少有三颗牙齿表现出严重敏感。在总共184颗牙齿中,69颗用Gluma Alternate治疗,58颗用Health Dent治疗,51颗用SMP治疗作为对照。在治疗前、局部应用药物后即刻、1周、1个月和6个月时,记录对冷空气刺激的敏感性作为反应。
Gluma Alternate和SMP在术前和术后疼痛评分之间均显示出敏感性显著降低(P < 0.05)。1周和6个月时的治疗后敏感性评分(0和1)没有差异。在Health-Dent组中,58颗牙齿中只有10颗显示敏感性降低。因此,其余48颗牙齿接受了Gluma脱敏剂的“挽救治疗”。在6个月观察期结束时,所有用Gluma Alternate、Gluma脱敏剂和SMP治疗的牙齿均未显示或仅有非常轻微的牙本质敏感。