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脊椎动物mRNA翻译保真度和效率的决定因素。

Determinants of translational fidelity and efficiency in vertebrate mRNAs.

作者信息

Kozak M

机构信息

Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Piscataway 08854.

出版信息

Biochimie. 1994;76(9):815-21. doi: 10.1016/0300-9084(94)90182-1.

Abstract

This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules.

摘要

本文综述了关于影响起始密码子选择准确性的机制的当前知识,并讨论了5′非编码区的结构特征对信使RNA分子翻译效率的影响。

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