Wachs G N, Maibach H I
Br J Dermatol. 1976 Sep;95(3):323-8. doi: 10.1111/j.1365-2133.1976.tb07021.x.
This double-blind study of an antibiotic coritcosteroid combination, the antibiotic alone and the corticosteroid alone, compared their clinical and microbiological effect in infected atopic dermatitis. Combination therapy reduced the mean scores for infection, inflammation and overall severity to a greater extent than the antibiotic or corticosteroid alone. The clinical and microbiological date are discussed in terms of relevance to clinical use.
这项关于抗生素与皮质类固醇联合用药、单独使用抗生素以及单独使用皮质类固醇的双盲研究,比较了它们在感染性特应性皮炎中的临床和微生物学效果。联合治疗在降低感染、炎症及总体严重程度的平均评分方面,比单独使用抗生素或皮质类固醇的效果更显著。根据与临床应用的相关性对临床和微生物学数据进行了讨论。