Feutrie M L, Hachulla E, Hatron P Y, Flipo R M, Brouillard M, Labalette P, Delaporte E, Wallaert B, Gosset D, Devulder B
Service de Médecine interne, Hôpital Claude Huriez, Lille.
Presse Med. 1994 Dec 10;23(39):1809-12.
Different diagnostic criteria for Behçet's disease are proposed in the literature. We compared the criteria proposed by Mason and Barnes with those proposed by the International Study Group and with those proposed by the Japanese committee.
This retrospective study included 41 patients with Behçet's disease according to the criteria set by Mason and Barnes. There were 16 patients of French origin and 25 patients of North African origin.
Genital ulcerations were more frequent in the North African population (p < 0.007) and typical Behçet skin lesions were more frequent in the French population (p < 0.021). Comparing the clinical data among the 41 patients with Behçet's disease according to the Mason-Barnes criteria revealed that only 83% met the criteria set by the International Study Group and only 54% the criteria of the Japanese committee. For the International Study Group criteria, the requirement for recurrent buccal ulcerations with at least 3 episodes over a 12 month period (a major criteria) was the most limiting element. Likewise, genital ulcerations were not always recurrent.
These findings confirm the variability of clinical manifestations of Behçet's disease with ethnic origin. Proposed diagnostic criteria vary depending on the study committee and should be used as diagnostic guidelines rather than as criteria required for positive diagnosis.
文献中提出了白塞病的不同诊断标准。我们将梅森（Mason）和巴恩斯（Barnes）提出的标准与国际研究小组提出的标准以及日本委员会提出的标准进行了比较。
这项回顾性研究纳入了41例根据梅森和巴恩斯制定的标准诊断为白塞病的患者。其中有16例法国裔患者和25例北非裔患者。
北非人群中生殖器溃疡更为常见（p < 0.007），而典型的白塞病皮肤病变在法国人群中更为常见（p < 0.021）。根据梅森 - 巴恩斯标准对41例白塞病患者的临床数据进行比较后发现，只有83%的患者符合国际研究小组制定的标准，只有54%的患者符合日本委员会的标准。对于国际研究小组的标准，要求在12个月内至少有3次复发性口腔溃疡发作（一项主要标准）是最具限制的因素。同样，生殖器溃疡并不总是复发。
这些发现证实了白塞病临床表现因种族起源而异。建议的诊断标准因研究委员会而异，应作为诊断指南而非确诊所需的标准使用。
