Knypl K, Brym E, Wacławek-Maczkowska J
Kliniki Nadciśnienia Tetniczego i Chorób Naczyń Ak. Med. w Warszawie.
Wiad Lek. 1993 Dec;46(23-24):898-901.
The effectiveness of hypotensive action and tolerance of Isoptin SR-240 were studied in 20 patients with primary arterial hypertension. The drug was used in doses 240-360 mg daily (mean dose 324 mg daily). Blood pressure returned to normal values in 12 (60%) out of 20 patients. In the remaining eight cases no blood pressure normalization was achieved. Side effects occurred in five patients. General worsening of wellbeing and easy tiring were most frequently observed. The results of the present work indicate that Isoptin SR-240 is an effective hypotensive drug, useful in the treatment of mild and moderate arterial hypertension.
对20例原发性高血压患者研究了缓释异搏定（Isoptin SR - 240）的降压效果及耐受性。药物用量为每日240 - 360毫克（平均每日剂量324毫克）。20例患者中有12例（60%）血压恢复至正常水平。其余8例未实现血压正常化。5例患者出现副作用。最常观察到的是全身健康状况恶化和易疲劳。本研究结果表明，缓释异搏定（Isoptin SR - 240）是一种有效的降压药物，可用于治疗轻、中度动脉高血压。
