Hannoun L, Christophe M, Ribeiro J, Nordlinger B, Elriwini M, Tiret E, Parc R
Service de chirurgie digestive, Hopital Saint Antoine, Paris.
Surg Gynecol Obstet. 1993 Dec;177(6):556-60.
Between January 1970 and December 1990, 223 patients underwent pancreaticoduodenal resection for pancreatic or periampullary tumors. Forty-four of these patients were 70 years of age or older and 179 patients were less than 70 years of age. In the older group, 27 patients were operated upon after 1986. The overall operative mortality rate was 9.0 percent and 2.5 percent during the last five years. The overall operative mortality rate was 4.5 percent in patients more than 70 years of age and 10 percent in those less than 70 years of age. The overall operative morbidity rate was 35 percent; 36 percent in patients more than 70 years of age and 35 percent in those less than 70 years of age. Survival was related to tumor histologic factors. For carcinoma of the pancreas, the survival rate at five years was 17 percent in patients more than 70 years of age and 19 percent in patients less than 70 years of age. For the ampullary carcinoma, the survival rate at five years was 38 percent in patients more than 70 years of age and 45 percent in patients less than 70 years of age. It can be concluded that, in a selected group, age is not a limiting factor for pancreaticoduodenal resection.
1970年1月至1990年12月期间，223例患者因胰腺或壶腹周围肿瘤接受了胰十二指肠切除术。其中44例患者年龄在70岁及以上，179例患者年龄小于70岁。在老年组中，27例患者于1986年后接受手术。总体手术死亡率在过去五年中为9.0%，最近五年为2.5%。70岁以上患者的总体手术死亡率为4.5%，70岁以下患者为10%。总体手术发病率为35%；70岁以上患者为36%，70岁以下患者为35%。生存率与肿瘤组织学因素有关。对于胰腺癌，70岁以上患者的五年生存率为17%，70岁以下患者为19%。对于壶腹癌，70岁以上患者的五年生存率为38%，70岁以下患者为45%。可以得出结论，在特定人群中，年龄不是胰十二指肠切除术的限制因素。
