Totaro R, Corridoni C, Marini C, Marsili R, Prencipe M
Clinica Neurologica, Università di L'Aquila.
Ital J Neurol Sci. 1993 Sep;14(6):451-4. doi: 10.1007/BF02339175.
Cerebral blood flow was measured by transcranial Doppler sonography (TCD) in 15 patients during and after an attack of paroxysmal atrial fibrillation. During the attack the mean flow velocity (MFV) was reduced significantly in the middle cerebral artery (p < 0.05) and nonsignificantly in the other arteries. The pulsatility index (PI) was reduced in all the arteries but not significantly. During the fibrillation phase the MFV and PI tended to decrease as the heart rate increased. None of the patients showed clinical signs of cerebral ischemia during the attacks. The absence of such signs despite the reduced cerebral blood flow in atrial fibrillation is probably due to the activation of mechanisms of autoregulation.
在15例阵发性心房颤动发作期间及发作后，采用经颅多普勒超声（TCD）测量脑血流量。发作期间，大脑中动脉的平均血流速度（MFV）显著降低（p<0.05），其他动脉的降低不显著。所有动脉的搏动指数（PI）均降低，但不显著。在颤动阶段，随着心率增加，MFV和PI趋于降低。发作期间，所有患者均未出现脑缺血的临床症状。尽管心房颤动时脑血流量减少，但未出现此类症状可能是由于自动调节机制的激活。
