基底脑循环的经颅彩色编码超声检查。115名志愿者的参考数据。

Transcranial color-coded sonography of the basal cerebral circulation. Reference data from 115 volunteers.

作者信息

Martin P J, Evans D H, Naylor A R

机构信息

Department of Neurology, Leicester Royal Infirmary, UK.

出版信息

Stroke. 1994 Feb;25(2):390-6. doi: 10.1161/01.str.25.2.390.

DOI:10.1161/01.str.25.2.390

PMID:7905680

Abstract

BACKGROUND AND PURPOSE

Transcranial color-coded sonography is a new development in noninvasive cerebral vascular imaging. Reference data using this technique are described.

METHODS

Blood velocities and pulsatility and resistance indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, vertebral, and basilar arteries in 115 volunteers after correction for the angle of insonation.

RESULTS

Of 1265 basal arterial segments, 1053 were insonated (83%). The vertebral (98%), basilar (92%), middle cerebral (84%), and posterior (P1) cerebral arteries (84%) were the most successfully insonated, with the anterior (73%) and posterior (P2) cerebral arteries (72%) the least successfully insonated. Mean and end-diastolic blood velocities decreased significantly with age in all vessels (middle cerebral artery mean velocity: 20 to 39 years, 74 cm/s [71-76]; > 60 years, 58 cm/s [55-61], P < .0001; mean with 95% confidence intervals), and peak systolic velocity decreased significantly except in the posterior (P2) cerebral artery. Blood velocities were higher in women except in the > 60-year group. Velocities showed the least interhemispheric asymmetry in the middle cerebral artery (r = .85 and r = .83, peak and mean velocities, respectively) and the greatest asymmetry in the posterior (P2) cerebral artery (r = .58 and r = .59, peak and mean velocities, respectively). Pulsatility and resistance indices increased significantly with age in all vessels (middle cerebral artery pulsatility index: 20 to 39 years, 0.84 [0.82-0.87], > 60 years, 0.97 [0.93-1.02], P < .0001; middle cerebral artery resistance index: 20 to 39 years, 0.55 [0.54-0.56], > 60 years, 0.62 [0.60-0.64], P < .0001).

CONCLUSIONS

Transcranial color-coded sonography can image the basal cerebral arteries and distinguish vertebral from basilar artery flow and enables pulsed Doppler interrogation with correction for the angle of insonation.

摘要

背景与目的

经颅彩色编码超声是无创脑血管成像的一项新进展。本文描述了使用该技术的参考数据。

方法

对115名志愿者的大脑前动脉、大脑中动脉、大脑后动脉、椎动脉和基底动脉进行了血流速度、搏动指数和阻力指数的测定，并对声束入射角进行了校正。

结果

在1265个基底动脉节段中，成功检测到1053个（83%）。椎动脉（98%）、基底动脉（92%）、大脑中动脉（84%）和大脑后动脉（P1段，84%）的检测成功率最高，大脑前动脉（73%）和大脑后动脉（P2段，72%）的检测成功率最低。所有血管的平均血流速度和舒张末期血流速度均随年龄显著降低（大脑中动脉平均血流速度：20至39岁，74 cm/s[71 - 76]；>60岁，58 cm/s[55 - 61]，P <.0001；平均值及95%置信区间），除大脑后动脉（P2段）外，收缩期峰值血流速度也显著降低。除60岁以上组外，女性的血流速度较高。大脑中动脉的血流速度半球间不对称性最小（峰值和平均血流速度的r值分别为0.85和0.83），大脑后动脉（P2段）的血流速度半球间不对称性最大（峰值和平均血流速度的r值分别为).58和0.59）。所有血管的搏动指数和阻力指数均随年龄显著增加（大脑中动脉搏动指数：20至39岁，0.84[0.82 - 0.87]；>60岁，0.97[0.93 - 1.02]，P <.0001；大脑中动脉阻力指数：20至39岁，0.55[0.54 - 0.56]；>60岁，0.62[0.60 - 0.64]，P <.0001）。