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Taxol: pharmacology, metabolism and clinical implications.

作者信息

Rowinsky E K, Wright M, Monsarrat B, Lesser G J, Donehower R C

机构信息

Division of Pharmacology and Experimental Therapeutics, Johns Hopkins Oncology Center, Baltimore, Maryland 21287.

出版信息

Cancer Surv. 1993;17:283-304.

PMID:7907949
Abstract
摘要

相似文献

1
Taxol: pharmacology, metabolism and clinical implications.
Cancer Surv. 1993;17:283-304.
2
The clinical pharmacology of paclitaxel (Taxol).紫杉醇(泰素)的临床药理学。
Semin Oncol. 1993 Aug;20(4 Suppl 3):16-25.
3
[Paclitaxel (taxol): a review of its antitumor activity and toxicity in clinical studies].[紫杉醇(泰素):临床研究中其抗肿瘤活性与毒性的综述]
Gan To Kagaku Ryoho. 1998 Mar;25(4):605-15.
4
Early phase studies with paclitaxel/low-dose carboplatin in patients with solid tumors.紫杉醇/低剂量卡铂用于实体瘤患者的早期研究。
Semin Oncol. 1996 Dec;23(6 Suppl 16):26-31.
5
Phase I and pharmacologic study of a 3-hour infusion of paclitaxel followed by cisplatinum and 5-fluorouracil in patients with advanced solid tumors.对晚期实体瘤患者进行紫杉醇3小时输注后顺铂和5-氟尿嘧啶治疗的I期和药理学研究。
Clin Cancer Res. 1999 Jul;5(7):1723-30.
6
[Paclitaxel (Taxol)--drug of choice in ovarian cancer].
Harefuah. 1996 Apr 15;130(8):557-60.
7
A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies.一项关于蛋白酶体抑制剂硼替佐米(PS - 341,万珂)与紫杉醇及卡铂联合应用于晚期恶性肿瘤患者的Ⅰ期及药理学研究。
Cancer Chemother Pharmacol. 2007 Feb;59(2):207-15. doi: 10.1007/s00280-006-0259-9. Epub 2006 Jun 9.
8
Paclitaxel pharmacology and other tumor types.紫杉醇药理学与其他肿瘤类型。
Semin Oncol. 1997 Dec;24(6 Suppl 19):S19-1-S19-12.
9
[Taxol in the treatment of ovarian neoplasm].[紫杉醇治疗卵巢肿瘤]
Zhonghua Fu Chan Ke Za Zhi. 1999 Jul;34(7):439-41.
10
[Taxol based chemotherapy in the treatment of advanced gastric cancer].[以紫杉醇为基础的化疗在晚期胃癌治疗中的应用]
Zhonghua Zhong Liu Za Zhi. 2004 Sep;26(9):562-4.

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Valproic acid induced differentiation and potentiated efficacy of taxol and nanotaxol for controlling growth of human glioblastoma LN18 and T98G cells.丙戊酸诱导分化并增强紫杉醇和纳米紫杉醇对人神经胶质瘤 LN18 和 T98G 细胞生长的抑制作用。
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Paclitaxel-2'-Ethylcarbonate prodrug can circumvent P-glycoprotein-mediated cellular efflux to increase drug cytotoxicity.紫杉醇-2'-碳酸乙酯前药可规避P-糖蛋白介导的细胞外排,以增强药物的细胞毒性。
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