Siebert W T, Westerman E L, Smilack J D, Bradshaw M W, Williams T W
Antimicrob Agents Chemother. 1976 Sep;10(3):467-9. doi: 10.1128/AAC.10.3.467.
A double-blind study with volunteers was performed to determine the incidence and severity of thrombophlebitis associated with cephalothin, cephapirin, cefamandole, and a water control. Although there were no statistical differences in the incidence of thrombophlebitis, cephalothin resulted in significantly more severe thrombophlebitis compared with the other agents.
对志愿者进行了一项双盲研究，以确定与头孢噻吩、头孢匹林、头孢孟多和一种对照液相关的血栓性静脉炎的发生率和严重程度。尽管血栓性静脉炎的发生率没有统计学差异，但与其他药物相比，头孢噻吩导致的血栓性静脉炎明显更严重。
