三种头孢菌素类抗生素相关血栓性静脉炎的比较
Comparison of thrombophlebitis associated with three cephalosporin antibiotics.
作者信息
Siebert W T, Westerman E L, Smilack J D, Bradshaw M W, Williams T W
出版信息
Antimicrob Agents Chemother. 1976 Sep;10(3):467-9. doi: 10.1128/AAC.10.3.467.
Abstract
A double-blind study with volunteers was performed to determine the incidence and severity of thrombophlebitis associated with cephalothin, cephapirin, cefamandole, and a water control. Although there were no statistical differences in the incidence of thrombophlebitis, cephalothin resulted in significantly more severe thrombophlebitis compared with the other agents.
摘要
对志愿者进行了一项双盲研究，以确定与头孢噻吩、头孢匹林、头孢孟多和一种对照液相关的血栓性静脉炎的发生率和严重程度。尽管血栓性静脉炎的发生率没有统计学差异，但与其他药物相比，头孢噻吩导致的血栓性静脉炎明显更严重。
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本文引用的文献
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Cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity.头孢孟多，一种具有异常广泛活性谱的头孢菌素抗生素。
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Relative incidence of phlebitis caused by continuous intravenous infusion of cephapirin and cephalothin.持续静脉输注头孢匹林和头孢噻吩所致静脉炎的相对发生率。
Antimicrob Agents Chemother. 1972 Sep;2(3):234-5. doi: 10.1128/AAC.2.3.234.
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Phlebitis associated with cephalosporins: cephapirin versus cephalothin.与头孢菌素相关的静脉炎：头孢匹林与头孢噻吩的比较。
Curr Ther Res Clin Exp. 1973 Feb;15(2):37-43.
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Double-blind controlled comparison of phlebitis produced by cephapirin and cephalothin.头孢匹林与头孢噻吩所致静脉炎的双盲对照比较
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