Mouchet J
Orstom, Paris, France.
Sante. 1994 Jul-Aug;4(4):257-62.
The availability of DDT led to a revolution in insect pest control. However, in the 1970's it was banned or its use restricted in many countries because it was accumulating in the environment. It was suggested that this could have a deleterious effect on human health. However, these effects, particularly carcinogenesis, have never been clearly proved in humans. Furthermore, accumulation is significantly lower in the tropical than temperature environment. DDT can therefore be continued to be used as a spray in houses, where it is sequestrated by mud walls. It is mainly used against anopheles (mosquitoes) for malaria control and phlebotomus (sand flies) for control of leishmaniasis. However, the value of DDT is restricted by the resistance of many vector species; and its excitatory-repellent effect which does not allow interruption of malaria transmission in highly endemic areas (for example Northern Cameroun).
滴滴涕的问世引发了害虫防治的一场革命。然而，在20世纪70年代，它在许多国家被禁止使用或其使用受到限制，因为它在环境中不断积累。有人认为这可能对人类健康产生有害影响。然而，这些影响，尤其是致癌作用，在人类身上从未得到明确证实。此外，热带地区的积累量明显低于温带环境。因此，滴滴涕可以继续作为房屋喷雾剂使用，它会被泥墙吸附。它主要用于防治按蚊（蚊子）以控制疟疾，以及白蛉（沙蝇）以控制利什曼病。然而，滴滴涕的价值受到许多病媒物种抗药性的限制；以及它的兴奋驱避作用，这使得在疟疾高度流行地区（如喀麦隆北部）无法中断疟疾传播。
