Ganz T
Will Rogers Institute Pulmonary Research Laboratory, University of California, Los Angeles 90024-1736.
New Horiz. 1993 Feb;1(1):23-7.
Macrophages and their secretory products play a central role in host defense against pathogenic microbes in the development of protective immunity, in pathogenesis of septic shock and of acute and chronic infections, and in the pathophysiology of wound healing, tissue remodeling, and fibrosis. This review provides a bird's-eye view of the vast literature of the macrophage.
巨噬细胞及其分泌产物在宿主抵御致病微生物、保护性免疫的形成、脓毒症休克以及急慢性感染的发病机制,以及伤口愈合、组织重塑和纤维化的病理生理学过程中发挥着核心作用。本文综述对巨噬细胞的大量文献进行了概述。