Fikree F F, Berendes H W
Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Bull World Health Organ. 1994;72(4):581-7.
Reported are the results of a community-based prospective study in four urban squatter settlements in Karachi that was carried out to assess the incidence of and risk factors for intrauterine growth retardation. The incidence of term intrauterine growth retardation was 24.4% among 738 singleton births. The socioeconomic and biological risk factors that were found to be statistically significant in a bivariate analysis were included in a logistic regression model to assess their independent effects. The major risk factors were low level of maternal education, paternal unemployment, consanguinity, short birth-to-conception intervals, short maternal stature, and low maternal weight. The population risk estimates suggest the desirability of public health interventions to improve maternal weight and birth spacing and of improvements in socioeconomic conditions, especially maternal education. Public education programmes to discourage consanguineous marriages should also be considered.
本文报告了在卡拉奇四个城市棚户区开展的一项基于社区的前瞻性研究结果,该研究旨在评估宫内生长迟缓的发生率及危险因素。在738例单胎分娩中,足月宫内生长迟缓的发生率为24.4%。在双变量分析中发现具有统计学意义的社会经济和生物学危险因素被纳入逻辑回归模型,以评估其独立影响。主要危险因素包括母亲教育水平低、父亲失业、近亲结婚、生育间隔短、母亲身材矮小和母亲体重低。人群风险评估表明,开展公共卫生干预以改善母亲体重和生育间隔,并改善社会经济状况,尤其是母亲教育水平,是很有必要的。还应考虑开展公共教育项目,劝阻近亲结婚。