Ponte F, Giuffré G, Giammanco R, Dardanoni G
Istituto di Clinica Oculistica, Università di Palermo, Italy.
Doc Ophthalmol. 1994;85(3):203-10. doi: 10.1007/BF01664928.
A case-control study was planned as a part of the Casteldaccia Eye Study in order to investigate about risk factors of ocular hypertension and glaucoma. Cases were 44 subjects with glaucoma or intraocular pressure of 24 mm Hg or more. Controls were 220 subjects with intraocular pressure of 20 mm Hg or less and no signs of glaucoma. A number of environmental, behavioral, systemic and ocular variables were studied. Among the others we investigated the following: sunlight exposure, smoking, alcohol intake, pregnancies, systemic hypertension, diabetes, use of corticosteroids, refractive status, anterior chamber depth, lens nuclear sclerosis, iris color and texture. After univariate analysis the use of ocular corticosteroids and antibiotics, myopia, shallow anterior chamber and myopic macular degeneration were associated with ocular hypertension or glaucoma. However, the logistic regression showed that only the use of ocular corticosteroids (odds ratio = 7.79) and the myopia (odds ratio = 5.56) were independently associated.
作为卡斯特尔达奇亚眼科研究的一部分，计划开展一项病例对照研究，以调查高眼压症和青光眼的危险因素。病例为44例患有青光眼或眼压在24毫米汞柱及以上的受试者。对照为220例眼压在20毫米汞柱及以下且无青光眼体征的受试者。研究了一系列环境、行为、全身和眼部变量。其中，我们调查了以下方面：阳光暴露、吸烟、饮酒、妊娠、系统性高血压、糖尿病、皮质类固醇的使用、屈光状态、前房深度、晶状体核硬化、虹膜颜色和纹理。单因素分析后发现，眼部皮质类固醇和抗生素的使用、近视、前房浅和近视性黄斑变性与高眼压症或青光眼有关。然而，逻辑回归显示，只有眼部皮质类固醇的使用（比值比=7.79）和近视（比值比=5.56）存在独立关联。
