Taghavy A, Hamer H
Department of Neurology, University of Erlangen, Germany.
Int J Neurosci. 1994 Jan-Feb;74(1-4):249-57. doi: 10.3109/00207459408987243.
We investigated 11 patients (63.1 +/- 10.9 y) after recovery (median: 3 days) from amaurosis fugax of 12.1 +/- 12.0 min duration with the method of pattern reversal visual evoked potentials (PVEPs) derived from Oz to Fz (Cz ground) after randomized monocular stimulation.
clear-cut cases with no hemispheric symptomatology, normal vision and normal cranial CT. The parameters were measured without knowing the affected eye and compared with age matched controls (n = 32). N80 latencies of the affected eyes were significantly prolonged (3.2 +/- 1.9 ms; p < .025) in comparison with the not affected eyes. The controls did not show such interocular difference. P100 latency behaved similarly but less prominently so (2.0 +/- 2.3 ms; p < .05; controls: p > .05). N80/P100 amplitude was reduced in 82% after stimulation of the affected side without reaching statistical significance. The 5 patients showing angiographically ipsilateral very tight stenosis of carotid artery (> 95%) behaved more prominently so in all 3 parameters. The findings indicate a damage of nerval tissue responsible for visual perception or a hemodynamic insufficiency under stimulus condition in affected eyes outlasting the clinical symptomatology for a certain period of time.
我们采用模式反转视觉诱发电位（PVEP）方法，在11例患者（年龄63.1±10.9岁）从持续时间为12.1±12.0分钟的一过性黑矇恢复（中位时间：3天）后，于随机单眼刺激后，从Oz记录到Fz（Cz接地）测量相关参数。入选标准：无半球症状、视力正常且头颅CT正常的明确病例。在不知道患眼的情况下测量参数，并与年龄匹配的对照组（n = 32）进行比较。与未受影响的眼睛相比，患眼的N80潜伏期显著延长（3.2±1.9毫秒；p < 0.025）。对照组未显示出这种眼间差异。P100潜伏期表现相似但不太明显（2.0±2.3毫秒；p < 0.05；对照组：p > 0.05）。刺激患侧后，82%的患者N80/P100波幅降低，但未达到统计学意义。5例血管造影显示同侧颈动脉极重度狭窄（> 95%）的患者在所有3个参数上表现更为明显。这些发现表明，在刺激条件下，患眼负责视觉感知的神经组织受损或存在血液动力学不足，且这种情况在临床症状消失后仍会持续一段时间。
