从致病性巴西诺卡氏菌中分离出的三种新的蒽环类相关还原化合物。

Three new reduced anthracycline related compounds from pathogenic Nocardia brasiliensis.

作者信息

Maeda A, Nagai H, Yazawa K, Tanaka Y, Imai T, Mikami Y, Kuramochi T, Yamazaki C

机构信息

Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.

出版信息

J Antibiot (Tokyo). 1994 Sep;47(9):976-81. doi: 10.7164/antibiotics.47.976.

DOI:10.7164/antibiotics.47.976

PMID:7928699

Abstract

Three new metabolites were isolated from a pathogenic bacterium, Nocardia brasiliensis IFM 0075 strain, a producer of a new anthracycline antibiotic (SO-075R1) and its mutant strain (IFM 0075-13-1). The structural studies showed that they are reduced anthracyline related compounds. Some biosynthetic routes of these metabolites were discussed.

摘要

从致病性巴西诺卡氏菌IFM 0075菌株（一种新型蒽环类抗生素（SO-075R1）的产生菌）及其突变菌株（IFM 0075-13-1）中分离出三种新的代谢产物。结构研究表明，它们是还原型蒽环类相关化合物。讨论了这些代谢产物的一些生物合成途径。