Sun M, Reed G W, Hill J O
Department of Pediatrics, Vanderbilt University, Nashville, Tennessee 37232.
J Appl Physiol (1985). 1994 Jun;76(6):2686-91. doi: 10.1152/jappl.1994.76.6.2686.
Whole room indirect calorimeters are among the most accurate devices for measurement of human energy expenditure and have provided useful data about determinants of total daily energy expenditure. However, a limitation of whole room indirect calorimeters has been the inability to detect acute (usually < 10-15 min) changes in energy expenditure. This precludes using these devices to study the acute effects of food, drugs, or exercise on energy expenditure. We describe modifications made to our whole room indirect calorimeter (respiratory chamber) to allow accurate measurement of energy expenditure over time periods as short as 1 min. The modifications involve changes in the system design and use of signal processing techniques. With these modifications, we can measure energy expenditure in 1-min intervals throughout the day. This allows accurate study of the acute effects of food, exercise, or drugs on energy expenditure in subjects moving freely inside the respiratory chamber. The ability to use respiratory chambers for these types of studies should improve our understanding of how body weight is regulated.
全室间接测热仪是测量人体能量消耗最精确的设备之一，它提供了有关每日总能量消耗决定因素的有用数据。然而，全室间接测热仪的一个局限性在于无法检测能量消耗的急性（通常<10-15分钟）变化。这使得无法使用这些设备来研究食物、药物或运动对能量消耗的急性影响。我们描述了对我们的全室间接测热仪（呼吸室）所做的改进，以允许在短至1分钟的时间段内准确测量能量消耗。这些改进涉及系统设计的改变和信号处理技术的应用。通过这些改进，我们可以全天每隔1分钟测量一次能量消耗。这使得能够准确研究食物、运动或药物对在呼吸室内自由活动的受试者能量消耗的急性影响。使用呼吸室进行这类研究的能力应该会增进我们对体重调节方式的理解。
