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狂犬病诊断中的小鼠接种试验:潜伏期小鼠的早期诊断。

The mouse inoculation test in rabies diagnosis: early diagnosis in mice during the incubation period.

作者信息

Webster W A, Casey G A, Charlton K M

出版信息

Can J Comp Med. 1976 Jul;40(3):322-5.

Abstract

Brain tissue from 64 rabies suspect specimens were inoculated intracerebrally into twenty 9-12 gm adult Swiss white mice. Two mice from each specimen were killed on specific days postinoculation and examined for the presence of rabies virus by the fluorescent antibody staining technique. In this way a positive diagnosis was made in the majority of cases between postinoculation days 4 and 12 when the incubation period of these same specimens ranged between eight and 20 days.

摘要

将来自64个狂犬病疑似标本的脑组织经脑内接种到20只体重9 - 12克的成年瑞士小白鼠体内。在接种后的特定日子,从每个标本中选取两只小鼠处死,并通过荧光抗体染色技术检测是否存在狂犬病病毒。通过这种方式,在大多数病例中,接种后4至12天做出了阳性诊断,而这些相同标本的潜伏期在8至20天之间。

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