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皮层结构中的节律产生、幅度调制和多路复用

Rhythmogenesis, amplitude modulation, and multiplexing in a cortical architecture.

作者信息

Kopell N, LeMasson G

机构信息

Department of Mathematics, Boston University, MA 02215.

出版信息

Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10586-90. doi: 10.1073/pnas.91.22.10586.

Abstract

In a network of excitatory and inhibitory neurons, hyperpolarization-activated inward currents can help to produce population rhythms in which individual cells participate sparsely and randomly. A shift in the activation curve of such a current changes the fraction of the cells participating in any given cycle of the population rhythm, thus changing the amplitude of the field potential. Furthermore, the frequency of the population rhythm remains relatively fixed over a substantial range of amplitudes, allowing the population rhythm to play a separate processing role from that of the individual components.

摘要

在一个由兴奋性和抑制性神经元组成的网络中,超极化激活内向电流有助于产生群体节律,其中单个细胞稀疏且随机地参与。这种电流激活曲线的偏移会改变参与群体节律任何给定周期的细胞比例,从而改变场电位的幅度。此外,群体节律的频率在相当大的幅度范围内保持相对固定,使得群体节律能够发挥与单个组件不同的处理作用。

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