酵母中的葡萄糖胺抗性。I. 初步遗传分析。
Glucosamine resistance in yeast. I. A preliminary genetic analysis.
作者信息
Ball A J, Wong D K, Elliott J J
出版信息
Genetics. 1976 Oct;84(2):311-7. doi: 10.1093/genetics/84.2.311.
Abstract
Mutants of the yeast Saccaromyces cerevisiae which can grow on glycerol medium in the presence of 0.05% D (+) glucosamine have been isolated. Genetic analysis of 13 of these glucosamine resistant (GR) mutants demonstrated two modes of inheritance. One group of mutants (GR 5, 6, 7, 8, 9 and 10) gave results characteristic of non-Mendelian inheritance and it is suggested that these mutants represent one or more new mitochondial loci. Four of the remaining mutants showed clear-cut Mendelian inheritance. These mutants fell into two complementation groups and subsequent mapping experiments demonstrated that two independent loci, gay 1 and gay 2, unlinked to each other or to the centromeres of chromosomes I, II, IV, VIII or IX, were responsible for conferring glucosamine resistance in these mutants.
摘要
已分离出酿酒酵母的突变体，这些突变体在含有0.05% D(+)葡糖胺的甘油培养基上能够生长。对其中13个葡糖胺抗性（GR）突变体进行的遗传分析显示出两种遗传模式。一组突变体（GR 5、6、7、8、9和10）给出了非孟德尔遗传特征的结果，提示这些突变体代表一个或多个新的线粒体基因座。其余突变体中的四个显示出明确的孟德尔遗传。这些突变体分为两个互补组，随后的定位实验表明，两个独立的基因座gay 1和gay 2，它们彼此不连锁，也不与染色体I、II、IV、VIII或IX的着丝粒连锁，负责赋予这些突变体葡糖胺抗性。
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1
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Biochem J. 1929;23(3):536-45. doi: 10.1042/bj0230536.
2
Replica plating and indirect selection of bacterial mutants.细菌突变体的影印培养和间接筛选
J Bacteriol. 1952 Mar;63(3):399-406. doi: 10.1128/jb.63.3.399-406.1952.
3
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