成年肝脏中调节糖酵解和糖异生的基因的转录调控。 - Suppr

Suppr

超能文献

Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver.

作者信息

Lemaigre F P, Rousseau G G

机构信息

Hormone and Metabolic Research Unit, University of Louvain Medical School, Brussels, Belgium.

出版信息

Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):1-14. doi: 10.1042/bj3030001.

DOI:10.1042/bj3030001

PMID:7945228

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1137548/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4c/1137548/0d7c49cede68/biochemj00078-0014-a.jpg

相似文献

Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver.成年肝脏中调节糖酵解和糖异生的基因的转录调控。

Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):1-14. doi: 10.1042/bj3030001.

[Regulation of the expression of hepatic genes coding the enzymes of glycolysis and gluconeogenesis].

Journ Annu Diabetol Hotel Dieu. 1996:37-53.

Control of glycolysis and gluconeogenesis in liver and kidney cortex.肝脏和肾皮质中糖酵解与糖异生的调控

Vitam Horm. 1967;25:1-87. doi: 10.1016/s0083-6729(08)60033-3.

Hormonal regulation of hepatic gluconeogenesis and glycolysis.

Annu Rev Biochem. 1988;57:755-83. doi: 10.1146/annurev.bi.57.070188.003543.

Regulation of gene expression by glycolytic and gluconeogenic enzymes.糖解和糖异生酶对基因表达的调控。

Trends Cell Biol. 2022 Sep;32(9):786-799. doi: 10.1016/j.tcb.2022.02.003. Epub 2022 Mar 14.

Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis.转录因子和辅激活因子控制肝糖异生的营养和激素调节。

Int J Biochem Cell Biol. 2012 Jan;44(1):33-45. doi: 10.1016/j.biocel.2011.10.001. Epub 2011 Oct 8.

[Role of enzymatic systems and regulatory mechanisms in homeostasis].[酶系统和调节机制在体内平衡中的作用]

Stud Cercet Med Interna. 1971;12(4):325-33.

Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis.肝脏糖异生和糖酵解调节的分子生理学

Annu Rev Physiol. 1992;54:885-909. doi: 10.1146/annurev.ph.54.030192.004321.

Differential gene expression in periportal and perivenous mouse hepatocytes.小鼠肝门周和肝静脉周肝细胞中的差异基因表达。

FEBS J. 2006 Nov;273(22):5051-61. doi: 10.1111/j.1742-4658.2006.05503.x. Epub 2006 Oct 20.

RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output.db/db 小鼠肝脏的 RNA 测序鉴定出 lncRNA H19 是糖异生和肝葡萄糖输出的关键调节因子。

Sci Rep. 2017 Aug 16;7(1):8312. doi: 10.1038/s41598-017-08281-7.

引用本文的文献

Metabolic reprogramming of glucose: the metabolic basis for the occurrence and development of hepatocellular carcinoma.葡萄糖的代谢重编程：肝细胞癌发生发展的代谢基础。

Front Oncol. 2025 Feb 6;15:1545086. doi: 10.3389/fonc.2025.1545086. eCollection 2025.

Specificity Proteins (SP) and Krüppel-like Factors (KLF) in Liver Physiology and Pathology.肝脏生理和病理中的特异性蛋白 (SP) 和 Krüppel 样因子 (KLF)。

Int J Mol Sci. 2023 Feb 28;24(5):4682. doi: 10.3390/ijms24054682.

Liver glucose metabolism in humans.人类肝脏中的葡萄糖代谢。

Biosci Rep. 2016 Nov 29;36(6). doi: 10.1042/BSR20160385. Print 2016 Dec.

pH-responsive, gluconeogenic renal epithelial LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule metabolism and function.pH响应性、糖异生肾上皮LLC-PK1-FBPase+细胞：一种用于研究近端肾小管代谢和功能的通用体外模型。

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F1-F11. doi: 10.1152/ajprenal.00067.2014. Epub 2014 May 7.

FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop.FOXO3 是糖皮质激素受体的靶标，并根据细胞 AMP 水平通过正反馈环调节 LKB1 及其自身的表达。

PLoS One. 2012;7(7):e42166. doi: 10.1371/journal.pone.0042166. Epub 2012 Jul 27.

Pyrrolidine dithiocarbamate enhances hepatic glycogen synthesis and reduces FoxO1-mediated gene transcription in type 2 diabetic rats.吡咯烷二硫代氨基甲酸盐可增强 2 型糖尿病大鼠肝糖原合成，并降低 FoxO1 介导的基因转录。

Am J Physiol Endocrinol Metab. 2012 Feb 15;302(4):E409-16. doi: 10.1152/ajpendo.00453.2011. Epub 2011 Nov 29.

Fish oil normalizes plasma glucose levels and improves liver carbohydrate metabolism in rats fed a sucrose-rich diet.鱼油可使喂食富含蔗糖饮食的大鼠的血糖水平正常化，并改善其肝脏碳水化合物代谢。

Lipids. 2012 Feb;47(2):141-50. doi: 10.1007/s11745-011-3623-4. Epub 2011 Nov 2.

Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation.盐诱导激酶通过控制固醇调节元件结合蛋白-1c（SREBP-1c）的磷酸化来调节肝脏脂肪生成。

J Biol Chem. 2009 Apr 17;284(16):10446-52. doi: 10.1074/jbc.M900096200. Epub 2009 Feb 25.

Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development.在肝脏发育过程中，肝细胞细胞核因子6（HNF-6）与HNF-4和PGC-1α协同作用的阈值水平是特定时间基因表达所必需的。

Mol Cell Biol. 2006 Aug;26(16):6037-46. doi: 10.1128/MCB.02445-05.

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice.肝细胞核因子3α缺陷小鼠的葡萄糖稳态受损与新生儿死亡率

Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10152-7. doi: 10.1073/pnas.96.18.10152.

本文引用的文献

Carbohydrate regulation of the rat L-type pyruvate kinase gene requires two nuclear factors: LF-A1 and a member of the c-myc family.大鼠L型丙酮酸激酶基因的碳水化合物调节需要两种核因子：LF-A1和c-myc家族的一个成员。

J Biol Chem. 1993 Jun 15;268(17):12787-95.

Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids.糖皮质激素受体 - cAMP反应元件结合蛋白的相互作用以及磷酸烯醇式丙酮酸羧激酶基因对糖皮质激素的反应。

J Biol Chem. 1993 Mar 15;268(8):5353-6.

An enhancer unit of L-type pyruvate kinase gene is responsible for transcriptional stimulation by dietary fructose as well as glucose in transgenic mice.L型丙酮酸激酶基因的一个增强子单元负责转基因小鼠中饮食果糖以及葡萄糖对转录的刺激作用。

FEBS Lett. 1993 Mar 8;318(3):269-72. doi: 10.1016/0014-5793(93)80526-z.

Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter.转录因子p91与表皮生长因子受体相互作用，并介导c-fos基因启动子的激活。

Cell. 1993 Sep 24;74(6):1135-45. doi: 10.1016/0092-8674(93)90734-8.

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors.一种由生长因子和细胞因子受体激活的常见核信号转导途径。

Science. 1993 Sep 24;261(5129):1739-44. doi: 10.1126/science.8397445.

Cloning and expression of novel isoforms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from bovine heart.牛心脏中6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶新亚型的克隆与表达

FEBS Lett. 1993 Sep 20;330(3):329-33. doi: 10.1016/0014-5793(93)80898-5.

Characterization of a hepatoma mRNA transcribed from a third promoter of a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-encoding gene and controlled by ets oncogene-related products.对一种肝癌信使核糖核酸（mRNA）的特性描述，该信使核糖核酸由6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶编码基因的第三个启动子转录，并受ets癌基因相关产物调控。

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8224-8. doi: 10.1073/pnas.90.17.8224.

Mammalian 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a bifunctional enzyme that controls glycolysis.哺乳动物6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶：一种控制糖酵解的双功能酶。

Prog Nucleic Acid Res Mol Biol. 1993;45:99-127. doi: 10.1016/s0079-6603(08)60868-5.

Expression of the liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA in FAO-1 cells.FAO-1细胞中肝脏6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶mRNA的表达

Biochem J. 1993 Jul 1;293 ( Pt 1)(Pt 1):173-9. doi: 10.1042/bj2930173.

Mammalian glucokinase and its gene.哺乳动物葡萄糖激酶及其基因。

Biochem J. 1993 Jul 1;293 ( Pt 1)(Pt 1):1-13. doi: 10.1042/bj2930001.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验