Check J H, Bollendorf A, Katsoff D, Kozak J
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden.
Am J Reprod Immunol. 1994 Aug;32(1):38-42. doi: 10.1111/j.1600-0897.1994.tb00876.x.
To determine the impact of the presence of antisperm antibodies (ASAs) in the cervical mucus of female partners in couples with unexplained poor postcoital tests (PCT). Furthermore, the efficacy of intrauterine insemination (IUI) in these same patients was determined by pregnancy rates (PRs).
Pregnancy rates following IUI in patients with infertility and poor postcoital tests, whether the cervical mucus was positive or negative for ASAs, were evaluated.
The 6-month PRs were similar in the ASA negative (40.5%) versus the positive (42.4%) group.
It appears that the antifertility effect of ASA may be mainly the immobilization of sperm in the cervical mucus, and thus, performing IUI may effectively correct the problem.
确定不明原因性交后试验（PCT）结果不佳的夫妇中，女性伴侣宫颈黏液中抗精子抗体（ASA）的存在所产生的影响。此外，通过妊娠率（PR）来确定这些患者进行宫内人工授精（IUI）的疗效。
评估了性交后试验结果不佳的不孕患者进行IUI后的妊娠率，无论其宫颈黏液ASA检测结果为阳性还是阴性。
ASA阴性组（40.5%）和阳性组（42.4%）的6个月妊娠率相似。
似乎ASA的抗生育作用可能主要是使精子在宫颈黏液中失活，因此，进行IUI可能有效地纠正这一问题。
