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[红毛五加对中枢神经系统作用的实验研究]

[An experimental study of the effect of Acanthopanax giraldii Harms on the central nervous system].

作者信息

Deng H Z, Hou L B, Sun S Y, Li S Y

机构信息

Nanfang Hospital of No 1 Military Medical University, Guangzhou.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Mar;19(3):171-4, 192.

PMID:7945845
Abstract

Experimental data indicated that Acanthopanax giraldii given intraperitoneally in mice had pronounced inhibitory effects on the CNS. It reduced the spontaneous activity, prolonged the hypnotic time of pentobarbital sodium and antagonised the amphetamine-induced hyperactivity. The results suggest that the sedative effect of A. giraldii is probably different from that of diazepam, but perhaps similar to that of reserpine.

摘要

实验数据表明,给小鼠腹腔注射红毛五加对中枢神经系统有明显的抑制作用。它能降低自发活动,延长戊巴比妥钠的催眠时间,并对抗苯丙胺引起的多动。结果表明,红毛五加的镇静作用可能与地西泮不同,但可能与利血平相似。

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