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沙棘籽油保肝作用及其机制的初步研究

[An preliminary study on hepato-protective action of seed oil of Hippophae rhamnoides L. (HR) and mechanism of the action].

作者信息

Cheng T J, Pu J K, Wu L W, Ma Z R, Cao Z, Li T J

机构信息

Lanzhou Medical College.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Jun;19(6):367-70, 384.

PMID:7945887
Abstract

The seed oil of Hippophae rhamnoides markedly inhibits the rise of MDA in liver of mice and rats induced by CCl4, AAP and ethyl alcohol, decreases significantly the activity of SGPT and SGOT, and markedly checks the depletion of GSH in liver of mice induced by AAP. The microscopic and electron-microscopic examination has shown that the seed oil can lighten liver injury.

摘要

沙棘籽油显著抑制由四氯化碳、对乙酰氨基酚和乙醇诱导的小鼠和大鼠肝脏中丙二醛的升高,显著降低谷丙转氨酶和谷草转氨酶的活性,并显著抑制对乙酰氨基酚诱导的小鼠肝脏中谷胱甘肽的消耗。显微镜和电子显微镜检查表明,沙棘籽油可减轻肝脏损伤。

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