Cheng T J, Qin H, Zhang P Y
Lanzhou Medical College.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Mar;14(3):162-4, 134.
Protective effect of Fengxiang Yigankang (FXYGK) capsule against hepatotoxicity induced by CCl4 and acetaminophen (AAP) was studied. It was found that the FXYGK capsule inhibited markedly malonic aldehyde (MDA) formation of liver induced by CCl4 and AAP. It blocked also depletion of reduced form of glutathione (GSH) of damaged liver induced by AAP. In addition, FXYGK could decrease serum alanine aminotransferase levels induced by CCl4 (P < 0.05). The results of histopathological examination showed that the FXYGK capsule (0.45, 0.9 and 1.8 g/kg) could also reduce significantly fatty degeneration of liver (P < 0.05).
