Chen D Y, Dovichi N J
Department of Chemistry, University of Alberta, Edmonton, Canada.
J Chromatogr B Biomed Appl. 1994 Jul 15;657(2):265-9. doi: 10.1016/0378-4347(94)00014-x.
Laser-induced fluorescence detection in a sheath flow cuvette is the most sensitive method of detecting fluorescent molecules for capillary electrophoresis. This manuscript demonstrates the detection of 50 yoctomoles (1 yoctomole = 1 ymol = 1 x 10(-24) mol) of rhodamine 6G. A 1-mW He-Ne laser (lambda = 543.5 nm) was used as the excitation source. This detection limit is a 10 times improvement compared to the previous state-of-the-art detection limit in separation science.
