Ozisik Y Y, Meloni A M, Stephenson C F, Peier A, Moore G E, Sandberg A A
Cancer Center of Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
Cancer Genet Cytogenet. 1994 Oct 15;77(2):125-8. doi: 10.1016/0165-4608(94)90227-5.
Cytogenetic analysis of 25 breast fibroadenomas (FA) showed clonal chromosome alterations in three cases. Insertion (12;?) (q15;?) and deletion (2) (q14q31 or q32) were detected as a sole change in cases 1 and 3, respectively. Case 2 displayed the karyotype 45,XX,t(1;8;16)(q25;q23;q22-23), add (7)(p14), rea(15), -17. The present findings are discussed together with the reports on FA in the literature.