Levine A, Tenhaken R, Dixon R, Lamb C
Plant Biology Laboratory, Salk Institute, La Jolla, California 92037.
Cell. 1994 Nov 18;79(4):583-93. doi: 10.1016/0092-8674(94)90544-4.
Microbial elicitors or attempted infection with an avirulent pathogen strain causes the rapid production of reactive oxygen intermediates. We report here that H2O2 from this oxidative burst not only drives the cross-linking of cell wall structural proteins, but also functions as a local trigger of programmed death in challenged cells and as a diffusible signal for the induction in adjacent cells of genes encoding cellular protectants such as glutathione S-transferase and glutathione peroxidase. Thus, H2O2 from the oxidative burst plays a key role in the orchestration of a localized hypersensitive response during the expression of plant disease resistance.
微生物激发子或用无毒病原体菌株进行的感染尝试会导致活性氧中间体的快速产生。我们在此报告，来自这种氧化爆发的H2O2不仅驱动细胞壁结构蛋白的交联，还作为受攻击细胞中程序性死亡的局部触发因素，并作为一种可扩散信号，用于诱导相邻细胞中编码细胞保护剂（如谷胱甘肽S-转移酶和谷胱甘肽过氧化物酶）的基因。因此，氧化爆发产生的H2O2在植物抗病性表达过程中局部过敏反应的协调中起关键作用。
