Granberg C, Meurman O
Orion Corporation, Orion Diagnostica, Espoo, Finland.
Eur J Clin Microbiol Infect Dis. 1994 Jun;13(6):512-5. doi: 10.1007/BF01974646.
Two new enzyme immunoassays for detection of rubella-specific IgM and IgG antibodies, Rubaset EIA-M and Rubaset EIA-G, were evaluated. Serum samples from 350 patients with or without rubella symptoms were tested. Rubaset EIA-M had a sensitivity of 98.0%, a specificity of 95.2% and an overall agreement of 96.8% compared with Rubazyme-M. Sera from patients with autoimmune diseases showed no false-positive reactivity. The corresponding values for Rubaset EIA-G were 98.5%, 94.8% and 96.9% respectively, compared with Rubazyme. Sera yielding discordant results were mainly acute-phase specimens from patients with confirmed rubella infection.
对两种用于检测风疹特异性 IgM 和 IgG 抗体的新型酶免疫测定法 Rubaset EIA-M 和 Rubaset EIA-G 进行了评估。检测了 350 例有或无风疹症状患者的血清样本。与 Rubazyme-M 相比，Rubaset EIA-M 的灵敏度为 98.0%，特异性为 95.2%，总体一致性为 96.8%。自身免疫性疾病患者的血清未显示假阳性反应。与 Rubazyme 相比，Rubaset EIA-G 的相应值分别为 98.5%、94.8% 和 96.9%。产生不一致结果的血清主要是确诊风疹感染患者的急性期样本。
