Samra Z, Soffer Y, Pansky M
Department of Microbiology, Chlamydia and Mycoplasma National Center, Beilinson Medical Center, Petach Tikva, Israel.
Eur J Epidemiol. 1994 Feb;10(1):69-73. doi: 10.1007/BF01717455.
To investigate the prevalence of genital mycoplasma (Ureaplasma urealyticum and Mycoplasma hominis) and Chlamydia trachomatis infections in infertile and fertile couples, 135 infertile couples from a male infertility clinic and 88 fertile couples from a prenatal care clinic were randomly screened. Semen, urethral and cervical smears were cultured for genital mycoplasma and chlamydia. Antichlamydia IgA, IgG and IgM antibodies were tested in blood and semen. Although the overall prevalence of Ureaplasma urealyticum was higher than that of Mycoplasma hominis, the prevalence of Mycoplasma hominis was significantly higher in the infertile men and women. The prevalence of Chlamydia trachomatis, positive culture was higher in infertile couples, but this difference was not significant. The prevalence of serum-specific IgG was significantly higher in infertile than in fertile women (11.9 vs 3.4%, p < 0.05). Specific semen IgA was significantly higher in infertile than in fertile men (8.9 vs 1.1%, p < 0.015). A low rate of concordance between partners was found in Mycoplasma and Chlamydia culture, and in the same patient between seminal IgA and urethral culture. In conclusion it is necessary to check both culture and serology findings in both partners.
为调查不育夫妇和可育夫妇中生殖支原体（解脲脲原体和人型支原体）及沙眼衣原体感染的患病率，对一家男性不育诊所的135对不育夫妇和一家产前保健诊所的88对可育夫妇进行了随机筛查。对精液、尿道和宫颈涂片进行生殖支原体和衣原体培养。检测血液和精液中的抗衣原体IgA、IgG和IgM抗体。虽然解脲脲原体的总体患病率高于人型支原体，但人型支原体在不育男性和女性中的患病率显著更高。沙眼衣原体培养阳性率在不育夫妇中更高，但差异不显著。不育女性血清特异性IgG的患病率显著高于可育女性（11.9%对3.4%，p<0.05）。不育男性精液特异性IgA显著高于可育男性（8.9%对1.1%，p<0.015）。在支原体和衣原体培养中，以及在同一患者的精液IgA和尿道培养之间，伴侣之间的一致性率较低。总之，有必要检查夫妇双方的培养和血清学结果。
