Norgren R B, Gao C
Department of Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha 68198-6395.
Dev Biol. 1994 Oct;165(2):735-8. doi: 10.1006/dbio.1994.1290.
Previous studies indicate that LHRH neurons of the septal-preoptic area originate in the olfactory epithelium. In the current study, we found that LHRH neurons entering the telencephalon from the olfactory nerve were not continuous with LHRH neurons in the thalamus. In addition, ablation of the olfactory placode eliminated LHRH neurons in the telencephalon but did not eliminate LHRH neurons in the thalamus. We propose that there are at least two sites of LHRH neuron production, the olfactory epithelium and the diencephalon.
先前的研究表明,隔区-视前区的促性腺激素释放激素(LHRH)神经元起源于嗅上皮。在本研究中,我们发现从嗅神经进入端脑的LHRH神经元与丘脑中的LHRH神经元并不连续。此外,嗅基板的切除消除了端脑中的LHRH神经元,但并未消除丘脑中的LHRH神经元。我们提出,促性腺激素释放激素神经元至少有两个产生部位,即嗅上皮和间脑。