Ferracane J L
Dental Materials Science, Oregon Health Sciences University, Portland 97201.
J Oral Rehabil. 1994 Jul;21(4):441-52. doi: 10.1111/j.1365-2842.1994.tb01158.x.
A significant amount of residual monomer or short chain polymers remain unbound in set composite material. Due to its potential impact on both the biocompatibility and the structural stability of the restoration, many investigators have studied the elution of these unbound molecules into aqueous media. The results of these studies suggest that elution of leachable components from composites is rapid, with the majority being released within a matter of hours. Weight losses of up to 2% of the mass of the composite have been reported under certain conditions. The studies have also shown that the extent and rate of elution of components from composites is dependent upon several factors. The quantity of leachables has been correlated to the degree of cure of the polymer network. The composition and solubility characteristics of the extraction solvent influence the kinetics and mechanism of the elution process. Elution is generally thought to occur via diffusion of molecules through the resin matrix, and is therefore dependent upon the size and chemical characteristics of the leachable species.
大量的残留单体或短链聚合物仍未结合在固化的复合材料中。由于其对修复体的生物相容性和结构稳定性都有潜在影响，许多研究人员研究了这些未结合分子在水性介质中的洗脱情况。这些研究结果表明，复合材料中可浸出成分的洗脱很快，大部分在数小时内就会释放出来。在某些条件下，已报道复合材料质量损失高达2%。研究还表明，复合材料中成分的洗脱程度和速率取决于几个因素。可浸出物的量与聚合物网络的固化程度相关。萃取溶剂的组成和溶解特性影响洗脱过程的动力学和机制。洗脱通常被认为是分子通过树脂基质扩散而发生的，因此取决于可浸出物质的大小和化学特性。
