Koduri P R, Patel A R, Bernstein H A
Department of Medicine, Cook County Hospital, Chicago, Illinois 60612.
J Natl Med Assoc. 1994 Sep;86(9):682-5.
Of 148 adults with sickle cell hemoglobin C (SC) disease seen at Cook County Hospital and Clinics, Chicago, Illinois, eight patients had coexistent noninsulin-dependent diabetes mellitus. The clinical findings were notable for the paucity of retinal vascular changes. No patient showed proliferative diabetic retinopathy; one patient showed background diabetic retinopathy consisting of a few microaneurysms. Six of the eight patients showed no lesions of proliferative sickle retinopathy. Coexistence of noninsulin-dependent diabetes mellitus and SC disease does not appear to have an additive adverse effect on the presence or severity of proliferative retinopathy in the affected patient.
在伊利诺伊州芝加哥市库克县医院及诊所就诊的148例镰状细胞血红蛋白C（SC）病成年患者中，有8例同时患有非胰岛素依赖型糖尿病。临床检查结果显示视网膜血管病变较少。没有患者出现增殖性糖尿病视网膜病变；1例患者出现了由少量微动脉瘤组成的背景性糖尿病视网膜病变。8例患者中有6例未出现增殖性镰状视网膜病变。非胰岛素依赖型糖尿病与SC病并存似乎对受影响患者增殖性视网膜病变的发生或严重程度没有叠加的不良影响。
