Lee E W, Dubin N
Department of Environmental Medicine, New York University Medical Center, NY 10010-2598.
Stat Med. 1994 Jun 30;13(12):1241-52. doi: 10.1002/sim.4780131206.
Although there is much literature on sample size determination for clinical trials or experiments with independent responses, there is a lack of methodology to obtain sample sizes for dependent outcomes. This paper presents a simple way to calculate sample size for estimating treatment effects and diagnostic accuracy in the case of correlated binary outcomes. The proposed weighted procedure also has use in estimation, whose advantages we demonstrate through simulation. Recommendations are made for practical application.
虽然有许多关于临床试验或具有独立反应的实验的样本量确定的文献，但缺乏用于获得相关结果样本量的方法。本文提出了一种简单的方法来计算样本量，用于估计相关二元结果情况下的治疗效果和诊断准确性。所提出的加权程序在估计中也有应用，我们通过模拟展示了其优点。并针对实际应用提出了建议。
